121 Dr. Michael Debakey Drive
121 Artisan Bistro offers delicious upscale comfort food featuring the freshest and finest ingredients
Come discover our unique dining experience! Serving up Italian favorites with a Southwest Louisiana flair, your 121 experience will take you from outstanding starters to decadent desserts. Try a hand cut, fresh steak cooked to perfection in our Stone Hearth Ovens, or a Signature Pasta like the Mona Lisa with fresh gulf shrimp & jumbo lump crab meat. We would love to serve you, you are the reason we love what we do!